Jun-Hyun金博士

研究方向和领域

空心聚合物纳米粒子药物运输车辆。我们感兴趣的是构建空心聚合物纳米粒子(hPNPs)用作选择性/特定药物运输载体,可以有很高的载药能力,简单的表面改性,和优秀的稳定性。这些高分子材料可以可靠地由使用传统的自由基聚合生长shell的聚合物monodipserse牺牲无机硅纳米颗粒大小可调。这种方法可以允许均匀可调,具有核壳结构的纳米粒子的合成及发展壳厚度从纳米到微米大小。交联后的聚合物壳通过酰胺和/或酯键,氟化硅芯的去除与稀释可以允许的形成稳定的壳交联hPNPs。交联过程可以允许hydrolytically降解和生物降解的形成酰胺/酯债券导致的有效释放封装体内的药物。因此,我们hPNPs为控释属性拥有一个额外的功能。这些结构可以高度中空心内含有小分子药物产生药物运输车辆。此外,表面功能化hPNPs与特定的/有选择性的针对群体将使他们作为药物运输车辆可以在疾病网站拥有有效的释放特性。我们的研究中,基于纳米材料和高分子化学的结合,提供了一个独特的复杂聚合物纳米结构的可靠的制备方法,将形成新一代的多功能药物传输系统。 Photochemical synthesis of nanoscale metal particles for catalytic applications. The main goal of this research is to prepare various metal nanoparticles (gold, silver, copper, palladium, and their alloys) possessing tunable absorption properties, and to examine their photothermal heating efficiency and catalytic activity in chemical reactions upon irradiation of a solar simulated light. Conventional spherical metal nanoparticles possess a strong but narrow absorption peak in the visible light area. Simply modified metal nanoparticles, however, can have a strong and wide absorption band across the visible to near infrared region, which largely covers the intense solar radiation spectrum on the Earth. As metal nanoparticles have a unique ability to absorb light energy and convert it into heat, the irradiation of these anisotropic metal nanoparticles with solar light can photothermally increase the temperature of the reaction media and the surface of the nanoparticles. Since most catalytic reactions take place on the surface of catalysts (e.g., a metal substance) and often require a moderate reaction temperature, employing these optically-active metal nanoparticles can enhance the reaction yields and reduce the reaction time without any electrical thermal input. Considering recent environmental concerns and the soaring demand for renewable energy this study is especially relevant. A thorough investigation of the structure-dependent absorption properties and the photothermal heating efficiency of metal nanomaterials and their catalytic activity in chemical reactions (including reduction, hydrogenation, homocoupling, Suzuki, and Ullman reactions) under a solar-simulated light allows for the development of highly effective, practical, and cost-efficient catalytic systems. Light-induced sysnthesis of gold nanoparticles Metal nanoparticle catalysis upon exposure to sunlight